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Salamanca woman jailed on murder, other charges

November 1, 2025

SALAMANCA — A city woman is facing murder and other felony charges after a death on River Street on Friday morning. The Salamanca Police Department re...

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Home Online Features Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing

Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing

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Spyre Therapeutics, Inc.

November 12, 2024

Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing

SPY001 was well tolerated with a favorable safety profile consistent with the anti-α4β7 class

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Local Sports, Sports

Randolph cheerleaders cap off successful fall, winter seasons

By HENRY BUCHAN Sports Editor

March 13, 2026

RANDOLPH — The Randolph Central School Cheerleaders wrapped up another successful year, continuing a tradition of spirit, dedication and competitive e...

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Featured, Local News, News, ...

Old Times Remembered for March 12-18

March 12, 2026

150 Years March 16, 1876: REVIVAL AT CATTARAUGUS — We have been enjoying a gracious revival in Cattaraugus during the past few weeks. The church has b...

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Cattaraugus County Source, Special Sections

Cattaraugus County Source 03-12-2026

mkeim@oleantimesherald.com

March 12, 2026

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Opinion

Kellen’s Pressing Issue

March 12, 2026

The Oscars The 98th Academy Awards are this Sunday, and awards season will come to a close with the who’s who of Hollywood gathering to pat themselves...

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Opinion

Henry’s Pressing Issue

March 12, 2026

I’ve always been drawn to March Madness. It’s meant to be the antithesis of logical thought. The person who wins your bracket will not have watched co...

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Cattaraugus County Source

Cattaraugus County Source, Special Sections

Cattaraugus County Source 03-05-2026

mkeim@oleantimesherald.com

March 5, 2026

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Spyre Therapeutics Announces Positive Interim Results from Phase 1 Healthy Volunteer Trial for SPY001, Its Novel Half-Life Extended anti-α4β7 Antibody for the Treatment of Inflammatory Bowel Disease, with a Half-Life of >90 Days Supporting the Potential for Both Q3M & Q6M Maintenance Dosing

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